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1

Total Synthesis of Rapamycin

Matthew L. Maddess, Miles N. Tackett, Hidenori Watanabe, Paul E. Brennan, Christopher D. Spilling, James S. Scott, David P. Osborn, Steven V. Ley

Journal:

Angewandte Chemie

Year:

2007

Language:

english

File:

PDF, 195 KB

english, 2007

2

Modeling a Crowdsourced Definition of Molecular Complexity

Sheridan, Robert P., Zorn, Nicolas, Sherer, Edward C., Campeau, Louis-Charles, Chang, Charlie (Zhenyu), Cumming, Jared, Maddess, Matthew L., Nantermet, Philippe G., Sinz, Christopher J., O’Shea, Paul

Journal:

Journal of Chemical Information and Modeling

Year:

2014

Language:

english

File:

PDF, 5.53 MB

english, 2014

3

Total Synthesis of Rapamycin

Matthew L. Maddess, Miles N. Tackett, Hidenori Watanabe, Paul E. Brennan, Christopher D. Spilling, James S. Scott, David P. Osborn, Steven V. Ley

Journal:

Angewandte Chemie International Edition

Year:

2007

Language:

english

File:

PDF, 195 KB

english, 2007

4

Total Synthesis of Rapamycin

Steven V. Ley, Miles N. Tackett, Matthew L. Maddess, James C. Anderson, Paul E. Brennan, Michael W. Cappi, Jag P. Heer, Céline Helgen, Masakuni Kori, Cyrille Kouklovsky, Stephen P. Marsden, Joanne Nor

Journal:

Chemistry - A European Journal

Year:

2009

Language:

english

File:

PDF, 955 KB

english, 2009

5

ChemInform Abstract: Enantioselective Allylation of β,γ-Unsaturated Aldehydes Generated via Lewis Acid Induced Rearrangement of 2-Vinyloxiranes.

Mark Lautens, Matthew L. Maddess, Effiette L. O. Sauer, Stephane G. Ouellet

Journal:

Year:

2002

File:

PDF, 38 KB

2002

6

Chemoselective Cross Metathesis of Bishomoallylic Alcohols: Rapid Access to Fragment A of the Cryptophycins (XIV).

Mark Lautens, Matthew L. Maddess

Journal:

Year:

2004

File:

PDF, 37 KB

2004

7

Preparation and Utility of Cyclic Enol Carbonates.

Matthew L. Maddess, Mark Lautens

Journal:

Year:

2004

File:

PDF, 31 KB

2004

8

Preparation of Homoallylic Homopropargylic Alcohols from 2-Vinyloxiranes.

Matthew L. Maddess, Mark Lautens

Journal:

Year:

2005

File:

PDF, 40 KB

2005

9

Preparation of Fused Polycyclic Vinylcyclopropanes via Radical Cascade Reactions.

Matthew L. Maddess, Emily Mainetti, Youssef Harrak, Celia Brancour, Priscille Devin, Anne-Lise Dhimane, Louis Fensterbank, Max Malacria

Journal:

Year:

2007

File:

PDF, 47 KB

2007

10

ChemInform Abstract: Enantioselective Allylation and Crotylation of in situ Generated β,γ-Unsaturated Aldehydes.

J. Adam McCubbin, Matthew L. Maddess, Mark Lautens

Journal:

Year:

2012

File:

PDF, 41 KB

2012

11

ChemInform Abstract: SNAr Reactions of 2-Methylthio-4-pyrimidinones in Pivalic Acid: Access to Functionalized Pyrimidinones and Pyrimidines.

Matthew L. Maddess, Rhiannon Carter

Journal:

Year:

2012

File:

PDF, 37 KB

2012

12

SNAr Reactions of 2-Methylthio-4-pyrimidinones in Pivalic Acid: Access to Functionalized Pyrimidinones and Pyrimidines

Maddess, Matthew, Carter, Rhiannon

Journal:

Year:

2012

Language:

english

File:

PDF, 218 KB

english, 2012

13

Enantioselective Synthesis of a Highly Substituted Tetrahydrofluorene Derivative as a Potent and Selective Estrogen Receptor Beta Agonist

Maddess, Matthew L., Scott, Jeremy P., Alorati, Anthony, Baxter, Carl, Bremeyer, Nadine, Brewer, Sarah, Campos, Kevin, Cleator, Ed, Dieguez-Vazquez, Alejandro, Gibb, Andrew, Gibson, Andrew, Howard, Me

Journal:

Organic Process Research & Development

Year:

2014

Language:

english

File:

PDF, 769 KB

english, 2014

14

Chemoselective Cross Metathesis of Bishomoallylic Alcohols: Rapid Access to Fragment A of the Cryptophycins

Lautens, Mark, Maddess, Matthew L.

Journal:

Organic Letters

Year:

2004

Language:

english

File:

PDF, 102 KB

english, 2004

15

Convenient Access to Functionalized Vinylcyclopentenols from Alkynyloxiranes

Wang, Letian, Maddess, Matthew L., Lautens, Mark

Journal:

Journal of Organic Chemistry

Year:

2007

Language:

english

File:

PDF, 90 KB

english, 2007

16

Preparation of Homoallylic Homopropargylic Alcohols from 2-Vinyloxiranes

Maddess, Matthew L., Lautens, Mark

Journal:

Organic Letters

Year:

2005

Language:

english

File:

PDF, 92 KB

english, 2005

17

Enantioselective Allylation of β , γ -Unsaturated Aldehydes Generated via Lewis Acid Induced Rearrangement of 2-Vinyloxiranes

Lautens, Mark, Maddess, Matthew L., Sauer, Effiette L. O., Ouellet, Stéphane G.

Journal:

Organic Letters

Year:

2002

Language:

english

File:

PDF, 58 KB

english, 2002

18

Total Synthesis of Cryptophycin Analogues via a Scaffold Approach

McCubbin, J. Adam, Maddess, Matthew L., Lautens, Mark

Journal:

Organic Letters

Year:

2006

Language:

english

File:

PDF, 143 KB

english, 2006

19

Highlights from the 42nd EUCHEM Conference on Stereochemistry, Bürgenstock, Switzerland, April 2007

Maddess, Matthew L., Kilbinger, Andreas F. M.

Journal:

Chemical Communications

Year:

2007

Language:

english

File:

PDF, 249 KB

english, 2007

20

Preparation of fused polycyclic vinylcyclopropanes via radical cascade reactions

Maddess, Matthew L., Mainetti, Emily, Harrak, Youssef, Brancour, C?lia, Devin, Priscille, Dhimane, Anne-Lise, Fensterbank, Louis, Malacria, Max

Journal:

Chemical Communications

Year:

2007

Language:

english

File:

PDF, 272 KB

english, 2007

21

Synthesis of 1,4-anhydro- D -xylitol heteroanalogues of the naturally occurring glycosidase inhibitor salacinol and their evaluation as glycosidase inhibitors

Ghavami, Ahmad, Johnston, Blair D, Maddess, Matthew D, Chinapoo, Sarah M, Jensen, Morten T, Svensson, Birte, Pinto, B Mario

Journal:

Canadian Journal of Chemistry

Year:

2002

Language:

english

File:

PDF, 102 KB

english, 2002

22

Enzymatic Resolution of Chlorohydrins for the Synthesis of Enantiomerically Enriched 2-Vinyloxiranes

McCubbin, J., Maddess, Matthew, Lautens, Mark

Journal:

Year:

2008

Language:

english

File:

PDF, 98 KB

english, 2008

23

Enantioselective Allylation and Crotylation of in situ Generated β,γ-Unsaturated Aldehydes

McCubbin, J., Maddess, Matthew, Lautens, Mark

Journal:

Year:

2011

Language:

english

File:

PDF, 125 KB

english, 2011

24

Preparation and Utility of Cyclic Enol Carbonates

Maddess, Matthew L., Lautens, Mark

Journal:

Year:

2004

Language:

english

File:

PDF, 179 KB

english, 2004

25

Carboxamide Spleen Tyrosine Kinase (Syk) Inhibitors: Leveraging Ground State Interactions to Accelerate Optimization

Ellis, J. Michael, Altman, Michael D., Cash, Brandon D., Haidle, Andrew M., Kubiak, Rachel L., Maddess, Matthew L, Yan, Youwei, Northrup, Alan B.

Journal:

ACS Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 636 KB

english, 2016

26

Refined Data Analysis Provides Clinical Evidence for Central Nervous System Control of Chronic Glaucomatous Neurodegeneration

Sponsel, William E., Groth, Sylvia L., Satsangi, Nancy, Maddess, Ted, Reilly, Matthew A.

Journal:

Translational Vision Science & Technology

Year:

2014

Language:

english

File:

PDF, 919 KB

english, 2014

27

Metal Catalyzed Synthesis of Dihydropyridobenzodiazepines

Maddess, Matthew L., Li, Chaomin

Journal:

Organometallics

Year:

2018

Language:

english

File:

PDF, 1.41 MB

english, 2018

28

Refined Frequency Doubling Perimetry Analysis Reaffirms Central Nervous System Control of Chronic Glaucomatous Neurodegeneration

Reilly, Matthew A., Villarreal, Analaura, Maddess, Ted, Sponsel, William Eric

Journal:

Translational Vision Science & Technology

Year:

2015

Language:

english

File:

PDF, 883 KB

english, 2015

29

Process Safety Considerations for the Supply of a High Energy Oxadiazole IDO1-Selective Inhibitor

Martinot, Theodore A, Ardolino, Michael J., Chen, Lu, Lam, Yu-hong, Li, Chaomin, Maddess, Matthew L, Muzzio, Daniel J., Qi, Ji, Saurí, Josep, Song, Zhiguo Jake, Tan, Lushi, Vickery, Thomas P., Yin, Ji

Journal:

Organic Process Research & Development

Year:

2019

Language:

english

File:

PDF, 596 KB

english, 2019

30

Development of Scalable Routes to 1-Bicyclo[1.1.1]pentylpyrazoles

Zarate, Cayetana, Ardolino, Michael, Morriello, Gregori J., Logan, Kaitlyn M., Kaplan, William P., Torres, Luis, Li, Derun, Chen, Meng, Li, Hongming, Su, Jing, Fuller, Peter, Maddess, Matthew L., Song

Journal:

Organic Process Research & Development

Year:

2020

File:

PDF, 1.51 MB

2020

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